This is a remote place, and I should say so plainly.
The reserve protects a range of habitats from dry foothills to juniper and spruce forest, up through alpine meadow to bare rock and snow. Wildlife includes brown bear, ibex and the elusive snow leopard, along with marmots in the meadows and golden eagles overhead. The Tien Shan, whose name means the Celestial Mountains, is one of the great Asian ranges, and even in its western outliers the scale is hard to take in: ridges stacked behind ridges, rivers cutting deep gorges, and walnut forests in the lower valleys that have been harvested for centuries.
For a motorcyclist, this is adventure country rather than touring country. Roads in the surrounding districts range from reasonable asphalt in the valleys to rutted gravel and river crossings in the hills, and weather can change in an hour from hot sunshine to cold rain or snow. There are no towns listed nearby, which tells you everything about the fuel and food situation: nothing is guaranteed, so carry fuel, water, a repair kit and a means of calling for help. Access to protected areas, border zones and some high passes may require permits, so check locally before you go, and go with another rider rather than alone.
The best season is June to September, when the passes are usually clear and the meadows are in flower, with the clearest views in the cooler days of early autumn. In the evening the valleys fill with the smell of juniper smoke and sheep, and the stars are extraordinarily bright. If you reach this place, you have earned it, and the right response is to ride out again carefully.